Research in our lab is focused on optical tools for detection of complex biological processes. We integrate nanotechnology, organic chemistry, and molecular biology tools to develop a wide range of probes for particular environments. We focus on tools that can improve the capabilities of current experimental methods, and on tools that fundamentally expand the nature of questions that can be asked in a biological context. There are three major programs that are currently underway:
These tools are all designed to investigate biological changes, in real-time, as they occur in living cells and animals. Through collaborations, we apply these cutting-edge technologies to important biological problems in human diseases.