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  Carnegie Mellon University

Bier Research Group

Presentations

Invited Talks

  1. Bier, Mark E. "Cryodetection MS of Polystyrene and Viral Particles." Flexible Package Conf. of the Society of Plastics Engineers, Houston, Texas, Feb. 24-27th, 2008.
  2. Bier, Mark E.; Sipe, David M.; Ozdemir, Abdil; Aksenov, Alex A.; Firek, Brian; Hendrix, Roger W. "Characterization of nanoscale materials and biomacromolecules via STJ cryodetector MALDI TOF mass spectrometry." Abstracts of Papers, 236th ACS National Meeting, Philadelphia, PA, United States, August 17-21, 2008.
  3. Bier, M.E. "The Analysis of Macromolecules Using a MALDI TOF Mass Spectrometer Incorporating a Superconducting Tunnel Junction (STJ) Cryodetector." Department of Biology, Niagara University, Feb. 2007.
  4. Bier, M.E. "Protein Analysis Using the Virtual Mass Spectrometry Laboratory." Department of Biology, Niagara University, Feb. 2007.
  5. Bier, M.E. "The Analysis of Macromolecules Using a MALDI TOF Mass Spectrometer Incorporating a Superconducting Tunnel Junction (STJ) Cryodetector." Department of Chemistry, University of Nebraska-Lincoln, Jan. 2007.
  6. Bier, Mark E.; Grabowski, Joseph J. "Virtual mass spectrometry laboratory: architecture, applications and evaluation." Abstracts of Papers, 230th ACS National Meeting, Washington, DC, United States, Aug. 28-Sept. 1, 2005.
  7. Bier, Mark E. "Mass Spectrometry of Proteins and the Virtual Mass Spectrometry Laboratory." BioSci 1590 Computational Biology at the University of Pittsburgh. February 23rd and 25th, 2005.
  8. Bier, Mark E.; Yang, Chungang; Grabowski, Joseph. "A novel mass spectrometry internet teaching tool." The 228th American Chemical Society National Meeting, Philadelphia, PA, August 22-26, 2004.
  9. Bier, Mark E.; Yang, Chungang; Yan, Lan; Grabowski, Joseph. "Protein identification using the virtual mass spectrometry laboratory." 35th Central Regional Meeting of the American Chemical Society, Pittsburgh, PA, October 19-22, 2003, 54.
  10. Bier, Mark E.; Yang, Chunguang "From 2D to 3D to 2D: the evolution of the Paul trap." 35th Central Regional Meeting of the American Chemical Society, Pittsburgh, PA, October 19-22, 2003, 45.
  11. Bier, Mark E.; Yang, Chunguang G.; Grabowski, Joseph J. "The virtual mass spectrometry laboratory and a polymer analysis case study." Polymeric Materials Science and Engineering, ACS National Meeting, New Orleans 2003.
  12. Bier, Mark E. "The basics of MALDI and ESI mass spectrometers for polymer analysis." Polymeric Materials Science and Engineering, ACS National Meeting New Orleans 2003.
  13. Bier, Mark E. "The Virtual Mass Spectrometry Laboratory and Real Biomolecule Analysis by MALDI-TOF MS." University of Torino, Torino, Italy, December 13, 2003.
  14. Bier, Mark E. "The Virtual Mass Spectrometry Laboratory for Protein Identification." University of Pittsburgh, Chemistry 3300, Advanced Topics Organic Chemistry I - Bioanalytical Mass Spectrometry, Prof. Joe Grabowski, April 2003.
  15. Bier, Mark E. "The Virtual Mass Spectrometry Laboratory for Protein Identification." University of Pittsburgh, Analytical Biochemistry class, Prof. John Hempel, October 2003.
  16. Bier, Mark E. "Rapid Scanning on a Quadrupole Ion Trap Mass Spectrometer." Comet Corporation, Flamatt, Switzerland, December 8, 2003.
  17. Bier, Mark E. "Proteomics and Mass Spectrometry: Instrumentation, Applications and Education." ACS Pittsburgh Section, September 24, 2002, Pittsburgh, PA.
  18. Bier, Mark E. "The Paul Ion Trap." Spectroscopy Society of Pittsburgh (SSP), Pittsburgh, PA, May 2002.
  19. Grabowski, J.; Bier, M.E. "Virtual Mass Spectrometry Laboratory." Section: NSF-Catalyzed Curriculum Development, Division of Chemical Education, 221st American Chemical Society National Meeting, in San Diego, CA, April, 2001.
  20. Bier, M. E. "Fundamentals of Electrospray Mass Spectrometry and Applications in Real-Time Reaction Monitoring from Micro-Reactors." University of Torino, Italy, September, 2000.
  21. Bier, M. E.; Lavery, K. "Monitoring Biomolecule Reactions in Real-Time Using Micro-Reactors and an Electrospray Mass Spectrometer." Fourteenth International Forum Process Analytical Chemistry, Las Vegas, NV, January, 2000.
  22. Bier, M. E. "Monitoring Biomolecule Reactions in Real-Time Using a Micro-Reactor and Electrospray-Mass Spectrometry." Mass Spectrometry Frontiers Symposium, Purdue University, West Lafayette, IN, October, 1999.
  23. Bier, M.E. "LC-MS-MS Instrumentation." Spectroscopy Society of Pittsburgh Mass Spectrometry Symposium, Carnegie Mellon University, Pittsburgh, PA, April, 1999.
  24. Bier, M.E. "Ion Trap Mass Spectrometry." Advanced Methods in Biological Mass Spectrometry, course at European Molecular Biology Laboratory, Heidelberg, Germany, October, 1997.
  25. Bier, M.E. "Flying Bio Ions." Department of Biological Science, Biological Journal Club, Carnegie Mellon University, 1997.
  26. Bier, M.E. "Analytical Applications of External Ionization with a Paul Ion Trap." 10th Informal Meeting on Mass Spectrometry, Padua, Italy, April 6-8, 1992.

Presentations

  1. Lanni, Eric J.; Zhu, Manzhou; Jin, Rongchao; Bier, Mark E.. Correlating MALDI-TOF mass spectrometry data of a Au25 nanoparticle with single crystal X-ray crystallography. Abstracts of Papers, 236th ACS National Meeting, Philadelphia, PA, United States, August 17-21, 2008 (2008)
  2. Bier, Mark E.; Aksenov, Alex A.; Ozdemir, Abdil; Sipe, David; Hendrix, Roger W.; Firek, Brian. MALDI TOF MS of biomacromolecular complexes using a superconducting tunnel junction (STJ) cryodetector. Abstracts of Papers, 234th ACS National Meeting, Boston, MA, United States, August 19-23, 2007 (2007),
  3. Aksenov, A.; Bier, .M E. Cryodetection MALDI TOF MS of Polystyrene up to the Mega Dalton Mass Range, Proceedings 55st ASMS Conference on Mass Spectrometry and Allied Topics, Indianapolis, IN, June 3-7, 2007.
  4. Ozdemir, Abdil; Aksenov, A.; Sipe, D.; Firek, B.; Hendrix., R.; Bier, .M E., The Analysis of Biomacromolecules Using a MALDI TOF Mass Spectrometer Incorporating a Superconducting Tunnel Junction (STJ) Cryodetector, Proceedings 55st ASMS Conference on Mass Spectrometry and Allied Topics, Indianapolis, IN, June 3-7, 2007.
  5. Bier, M.E.; VanHassel, E., Lanni, Eric J. and Liu A.A. Membrane Probes Incorporating Electrospray Ionization for the Analysis of Volatile Organic Compounds in Water and Air, International Conference on Mass Spectrometry, Prague, CR, August 27 - Sept 1, 2006.
  6. Bier, M.E.; Grabowski, J.J. Teach Protein Identification, Polymer Analysis and the Analysis of Cocaine in Hair Using an Internet Based Mass Spectrometry Lab Proceedings 54st ASMS Conference on Mass Spectrometry and Allied Topics, Seattle, Washington, 2006.
  7. VanHassel, Emily; Bier, Mark E.. Analysis of Volatile Organic Compounds in Water via an ESI Membrane Probe, Proceedings 53rd ASMS Conference on Mass Spectrometry and Allied Topics, Montreal, San Antonio, TX, June 5-9, 2005.
  8. Grabowski, Joseph J. and Bier, Mark E. "Teaching mass spectrometry methods via virtual instrumentation combined with case studies" The 228th American Chemical Society National Meeting, Philadelphia, PA, August 22-26, 2004.
  9. Bier, Mark E.; Yang, Chunguang G.; Grabowski, Joseph J. The virtual mass spectrometry laboratory and a polymer analysis case study. Polymeric Materials Science and Engineering 2003, 88, 70.
  10. Bier, Mark E. The basics of MALDI and ESI mass spectrometers for polymer analysis. Polymeric Materials Science and Engineering 2003, 88, 17-18.
  11. Grabowski, J; Bier, M.E. Mass Spectrometry Experience for Everyone Using Case Studies and a Virtual Laboratory, Federation of Analytical Chemistry and Spectroscopy Societies, Ft. Lauderdale, FL 2003.
  12. Sparvero, L.J.; Hong, Chang-Sook; Glorioso, J.; Bier, Mark E. Characterization of the Digestion of Amyloid Beta-Peptide by Neprilysin Using MALDI-TOF MS, Science 2003, University of Pittsburgh, Pittsburgh, PA, 2003.
  13. Bier, Mark E., The Virtual Mass Spectrometry Laboratory and the Protein Identification Case Study, Information Society and Education, Proceedings of the International Conference of Information and Communication Technologies in Education (ICTE2002) Badajoz, Spain 2003, 1(1) 134-139.
  14. Sparvero, L.J.; Hong, Chang-Sook; Glorioso, J.; Bier, Mark E. Characterization of the Digestion of Amyloid Beta-Peptide by Neprilysin Using MALDI-TOF MS, Proceedings 51st ASMS Conference on Mass Spectrometry and Allied Topics, Montreal, Canada 2003.
  15. Bier, M.E.; Grabowski, J. The Virtual Mass Spectrometry Laboratory, Proceedings 49th ASMS Conference on Mass Spectrometry and Allied Topics, Chicago May 27-31, 2001.
  16. Balasubramani. M.; Dong, S.; Halfter, W.; Bier, M.E. Analysis of Basal Lamina Proteins by MALDI-MS and Capillary LC ESI-MS-MS, Proceedings 49th ASMS Conference on Mass Spectrometry and Allied Topics, Chicago May 27-31, 2001.
  17. Pu, L.; Lazo, J.; Bier, M.E. Determination of the Binding of Cdc25A Catalytic Domain by Antiproliferative Quinones Using MALDI-MS and Capillary LC-ESI-MS, Proceedings 49th ASMS Conference on Mass Spectrometry and Allied Topics, Chicago May 27-31, 2001.
  18. Lemus, R.; Bier, M. E.; Lukinskeine, L.; Lind, L.; Karol, M. Development of an Immunoassay to Detect 1,6-Hexamethylene Diisocyanate for Biomonitoring of Workers, Society of Toxicology Conference 40th Annual Meeting, San Francisco, California, March 25–29, 2001.
  19. Pu, L.; Bier, M.E.; Southwick, E.C.; Cooley, K.A.; Lazo, J.S. Binding and Inhibition of CDC25A Catalytic Domain by Antiproliferative Naphthoquinones, Proceedings of the American Association for Cancer Research, New Orleans, LA March 24-28, 2001, 42, 927.
  20. Bier, M. E.; Lavery, K.; Conlin, L. Monitoring Biomolecule Reaction Rates in Real-Time Using a Micro-reactor and an Electrospray Mass Spectrometer, Advances in Mass Spectrometry 2001, 15, 523-524.
  21. Bier, M. E.; Lemus, R.; Lukinskeine, L.; Lind, L.; Karol, M. Adducts of Human Serum Albumin with 1,6-Hexamethylene Diisocyanate Detected by MALDI-TOF-MS for Use in Biomonitoring, Proceedings 48th ASMS Conference on Mass Spectrometry and Allied Topics, Long Beach, CA. June 11-15, 2000.
  22. Bier, M. E.; Kanabe, E.; Lavery, K. Monitoring the Real-Time Enzymatic Digestion of Peptides with an Electrospray Mass Spectrometer, Proceedings 47th Conference on Mass Spectrometry and Allied Topics, Dallas, Texas, June 13-17, 1999.
  23. Arnott, D.; King, K.; Bier, M.E.; Land, A.; Stults, J. The Identification of Proteins Associated with Hypertrophy of Cardiomyocytes by 2D Gel Electrophoresis Combined with Microcapillary LC-MS and Tandem MS, Proceedings 43rd Conference on Mass Spectrometry and Allied Topics, Atlanta, Georgia, May 21-26, 1995, 31.
  24. Strife, R.J.; Schwartz, J.; Bier, M.E.; Zhou, J. Electrospray-Ion Trap MSn for Structure Elucidation of Surfactants, Proceedings 43rd Conference on Mass Spectrometry and Allied Topics, Atlanta, Georgia, May 21-26, 1995, 160.
  25. Lane, W.S.; Land, A.; Jardine, I.; Bier, M.E. Identification of proteins Using LC-MS-MS on an Ion Trap Mass Spectrometer, Proceedings 43rd Conference on Mass Spectrometry and Allied Topics, Atlanta, Georgia, May 21-26, 1995, 649.
  26. Gillece-Castro, B.L.; Arnott, D.; Bier, M.E.; Land, A.; Stults, J. Peptide Phosphorylation Site Identification: A New Method Based on Ion Trap Mass Spectrometry, Proceedings 43rd Conference on Mass Spectrometry and Allied Topics, Atlanta, GA, May 21-26, 1995, 302.
  27. Kanai, M.; Seta, K.; Nakayama, H.; Isobe, T.; Okuyama, T.; Land, A.; Bier, M.E. HPLC-ESI Ion Trap MS-MS Analysis of Protein Separated by 2D-PAGE, Proceedings 43rd Conference on Mass Spectrometry and Allied Topics, Atlanta, GA, May 21-26, 1995, 616.
  28. Baldwin, S.W.; Stoney, K.; Land, A.P.; Bier, M.E.; Wheeler, K. Peptide Mapping by LC-MS-MS Using a Triple Quad or Ion Trap Spectrometer, Proceedings 43rd Conference on Mass Spectrometry and Allied Topics, Atlanta, Georgia, May 21-26, 1995, 652.
  29. Taylor, D.; Schwartz, J.; Zhou, J.; James, M.; Bier, M.E.; Korsak, A.; Stafford, G. Application of Tailored Waveform Generation to the Quadrupole Ion Trap, Proceedings 43rd Conference on Mass Spectrometry and Allied Topics, Atlanta, Georgia, May 21-26, 1995, 1103.
  30. Strife, R.J.; Schwartz, J.; Bier, M.E.; Zhou, J. Electrospray-Ion Trap for Structure Elucidation of Anionics, Proceedings 43rd Conference on Mass Spectrometry and Allied Topics, Atlanta, Georgia, May 21-26, 1995, 1113.
  31. Schwartz, J.; Bier, M.E.; Taylor, D.; Zhou, J.; Syka, J.E.P.; James, M.; Stafford, G. Technological Aspects of a New LC-MSn Quadrupole Ion Trap, Proceedings 43rd Conference on Mass Spectrometry and Allied Topics, Atlanta, Georgia, May 21-26, 1995, 1114.
  32. Johnson, E.K.; Schwartz, J.C.; Taylor, D.M.; Bier, M.E.; Ragsdale, J. Novel Technologies and Enhanced Features for GC-MS-MS Proceedings 43rd Conference on Mass Spectrometry and Allied Topics, Atlanta, Georgia, May 21-26, 1995, 1115.
  33. Stoney, K.; Nugent, K.; Land, A.; Bier, M.E.; Schwartz, J.; Wheeler, K. Automation of Rapid, High Sensitivity Pharmacokinetics Assays by LC-MS-MS Proceedings 43rd Conference on Mass Spectrometry and Allied Topics, Atlanta, Georgia, May 21-26, 1995, 861.
  34. Bier, M.E.; Schwartz, J.C.; Zhou, J.; Syka, J.E.P.; Taylor, D.; Land, A. James, M.; Fies, B. Peptide Sequencing Using Fast MS and MS-MS Scan Rates on a Capillary LC-Quadupole Ion Trap Proceedings 43rd Conference on Mass Spectrometry and Allied Topics, Atlanta, Georgia, May 21-26, 1995, 988.
  35. Bier, M.E.; Schwartz, J.C.; Zhou, J.; Syka, J.E.P.; Taylor, D.; Syka, J.E.P.; James, M.; Stafford, G. Peptide Sequencing Using Fast MS and MS-MS Scan Rates on a Capillary LC-Quadrupole Ion Trap Proceedings 43rd Conference on Mass Spectrometry and Allied Topics, Atlanta, Georgia, May 21-26 1995, 1117.
  36. Bier, M.E.; Louris, D.M.; Taylor, D.M.; Schwartz, J.C. Uhrich, M.D. The Reduction of Matrix Effects in Quadrupole Ion Trap Mass Spectrometry, Proceedings 41st Conference on Mass Spectrometry and Allied Topics, San Francisco, CA, May 31-June 4, 1993, 456a.
  37. Bier, M.E.; Schwartz, J.C.; Jardine, I.; Stafford, G. Matrix-Assisted Laser Desorption Quadrupole Mass Spectrometry Proceedings 40th Conference on Mass Spectrometry and Allied Topics, Washington, DC, May 31- June 5, 1992, 1017.
  38. Bier, M.E.; Hartford, R.E.; Herron, J.R.; Stafford, G. Coupling a Particle Beam and a Thermospray Interface to a Quadrupole Ion Trap Mass Spectrometer, Proceedings 39th Conference on Mass Spectrometry and Allied Topics Nashville, TN, May19-24, 1991, 538.
  39. Bier, M.E. Introduction of Liquid Solutions in an Ion Trap Mass Spectrometer Using a Three-Stage Particle Beam Interface, Ion Trapping in Mass Spectrometry, American Society for Mass Spectrometry, Sanibel Island, FL, January 28-13, 1990.

Number of Presentations Prior to 1990:

  • American Society for Mass Spectrometry: 3
  • American Chemical Society: 1
  • Federation of Analytical Chemistry and Spectroscopy Societies: 1

Mark E. Bier

Research Professor and Director, Center for Molecular Analysis

Department of Chemistry
Carnegie Mellon University
Mellon Institute
4400 Fifth Ave.
Pittsburgh, PA 15213

mbier@andrew.cmu.edu
412-268-3540 (office)
412-268-1061 (fax)

Office: MI 555