Contact Information:
Mellon Institute 546
4400 Fifth Avenue
Pittsburgh, PA 15213
Lab: (412) 268-5059
Email: meierk@andrew.cmu.edu

Research Interests and Current Projects:
My research interests lie at the intersection between bioinorganic, biochemical and biomedical studies that incorporate Mössbauer and EPR spectroscopy. I am currently working on a variety of projects which utilize Mossbauer, EPR and Density Functional Theory calculations to help elucidate the chemical properties and structures of complexes that are important in oxygen activation. A few of my most recent projects (in collaboration with the Que and Lipscomb labs at the University of Minnesota) have focused on the bioinorganic spectroscopy of biomimetic peroxo intermediates, high-valence complexes, and the enzyme homoprotocatechuate 2,3 dioxygenase (HPCD).

Education:
Allegheny College, Meadville, PA
• Bachelor of Science Degree in Physics
• August 2005- May 2009
• Minor: Philosophy
Carnegie Mellon University, Pittsburgh, PA
• First year graduate student
• August 2010-present

Research Experience:
1) Allegheny College Physics Department, Meadville, PA
• Fall 2008-Spring 2009
• Worked with Dr. Doros Petasis
• Two-semester long study of spin crossover systems of Prussian Blue analogs with Fe-Ru cores.
• Study will look at the effects of temperature perturbations and solvent additions to [Fe(tmphen)2]3[Ru(CN)6]2, using electron paramagnetic resonance spectroscopy and UV-Vis spectrophotometry.
• Research presented at the March 2009 APS Conference in Pittsburgh, PA.
2) University of Pittsburgh School of Medicine, MBSB department, Pittsburgh, PA
• Summer 2008, Summer 2009
• Worked with Dr. Rieko Ishima and post-doctoral fellow Joseph Walsh
• Researched effects on protein structure and backbone dynamics in the presence and absence of alignment medium.
• Research presented at the University of Pittsburgh Summer Undergraduate Research Conference.
3) Allegheny College Physics Department, Meadville, PA
• Spring 2008
• Worked with Professor Adele Poynor
• Lab-based study using Surface Plasmon Resonance with the intention of creating and characterizing mixed hydrophobic and hydrophilic surface layers

Publications:
1) Walsh, Joseph; Meier, Katlyn; Ishima, Rieko; Gronenborn, Angela M. NMR Studies on Domain Diffusion and Alignment in Modular GB1 Repeats. Biophysical Journal. October 2010, 99, 2636-2646.
2) Li, Feifei; Meier, Katlyn K.; Cranswick, Matthew A.; Charkrabarti, Mrinmoy; Van Heuvelen, Katherine; Münck, Eckard; Que Jr., Lawrence. Characterization of a High-Spin Nonheme Iron(III)-Hydroperoxo Intermediate and Its Conversion to an Iron(IV)-oxo Complex. J. Am. Chem. Soc., near resubmission.

Presentations:
1) K. Meier, T. Nocera, R. Abood, M. Chen M, M. Hilfiger, D. Petasis, C. Achim, K. Dunbar. Electron Paramagnetic Resonance Spectroscopic Studies of Cyanide-Bridged Fe/Os and Fe/Ru Clusters. Poster session presented at: 2009 APS March Meeting; 2009 March 16-20; Pittsburgh, Pennsylvania.
2) K. Meier, J. Walsh, R. Ishima. Determination of Backbone Dynamics in Single and Dual Domain Protein GB1: Comparison in the Presence and Absence of Alignment Media. Research was presented at: University of Pittsburgh Summer Undergraduate Research Conference; 2008 August 1; Pittsburgh, Pennsylvania.
3) K. Meier, J. Walsh, R. Ishima. Determination of Backbone Dynamics in Single and Dual Domain Protein GB1: Comparison in the Presence and Absence of Alignment Media. Research was presented at: Allegheny College Inaugural Symposium; 2008 October 17; Meadville, Pennsylvania.