Associate Professor of Chemistry and Biomedical Engineering
Biomaterials, Materials Chemistry, Polymer Science, Tissue Engineering
Research in the Washburn Group is on problems at the interface of materials chemistry and biology. Our primary focus has been the development of materials that locally control inflammation in tissues by neutralizing the soluble signaling proteins that mediate these responses. Composed of antibodies conjugated to high molecular weight polymer constructs, these materials have been shown to be active in a broad range of medical applications. Other areas of interest include development of complex fluids based on hyaluronic acid, biomimetic adhesives, and polymers derived from renewable resources.
|2004–present||Assistant Professor of Chemistry and Biomedical Engineering, Carnegie Mellon University|
|2000–2004||Research Chemist, Polymers Division, National Institute of Standards and Technology|
|1998–2000||Post-Doctoral Associate, Department of Chemical Engineering and Materials Science, University of Minnesota|
|1998||Ph.D., Chemistry, University of California (Berkeley)|
|1993||B.S., Chemistry, University of Illinois at Urbana-Champaign|
|2010||Coulter Foundation Translational Research Award|
|2005||3M Non-Tenured Faculty Grant|
Cytokine binding by polysaccharide-antibody conjugates. Sun LT, Buchholz KS, Lotze MT, Washburn NR. Mol Pharm. DOI: 10.1021/mp100150z
Design principles for cytokine-neutralizing gels: Cross-linking effects. Sun LT, Bencherif SA, Gilbert TA, Lotze MT, Washburn NR. Acta Biomater. DOI: 10.1016/j.actbio.2010.06.029
Biological activities of cytokine-neutralizing hyaluronic acid-antibody conjugates. Sun LT, Bencherif SA, Gilbert TA, Farkas AM, Lotze MT, Washburn NR. Wound Repair & Regeneration, 2010, 18: 302-10.
Complex fluids based on methacrylated hyaluronic acid. Prata JE, Barth TA, Bencherif SA, Washburn NR. Biomacromolecules, 2010, 11: 769-75.
Teaching Technological Innovation and Entrepreneurship in Polymeric Biomaterials. Washburn NR. J Biomed Mater Res A. 2010.
Enhanced Wet Adhesion and Shear of Elastomeric Micro-Fiber Arrays with Mushroom Tip Geometry and a Photopolymerized p(DMA-co-MEA) Tip Coating. Glass P, Chung H, Washburn NR, Sitti M. Langmuir. 2010.
Synthesis by AGET ATRP of degradable nanogel precursors for in situ formation of nanostructured hyaluronic acid hydrogel. Bencherif SA, Washburn NR, Matyjaszewski K. 2009; 10: 2499-507.